Characteristics | Details |
---|---|
Active Ingredients | Sildenafil 100mg and Vardenafil 20mg |
Administration | Oral Tablets |
Duration of Effect | Up to 6 hours |
Onset of Action | 30 to 60 minutes |
Price Range | $10 – $15 per tablet |
Visit Silvitra Site |
Pharmacokinetics
Silvitra, combining Sildenafil and Vardenafil, operates through a synergistic action. The pharmacokinetics of both agents must be understood for optimal results. Sildenafil 100mg is rapidly absorbed, reaching peak plasma concentrations within 30 to 120 minutes. Vardenafil 20mg shares similar kinetics with peak levels occurring in the same timeframe. Both substances undergo hepatic metabolism, predominantly via cytochrome P450 enzymes. Their elimination half-lives are approximately 4 to 5 hours, which facilitates their temporary effects.
The presence of food can delay the absorption of Sildenafil, impacting its onset of action. In contrast, Vardenafil’s absorption remains less influenced by dietary intake. This combination targets rapid and sustained enhancement of erectile function.
Mechanism of Action
Silvitra exerts its effects by inhibiting phosphodiesterase type 5 (PDE5), an enzyme responsible for the breakdown of cyclic guanosine monophosphate (cGMP). During sexual stimulation, nitric oxide is released, increasing cGMP levels and leading to smooth muscle relaxation in the corpus cavernosum. This action results in increased blood flow and the facilitation of an erection.
The dual action of Sildenafil 100mg and Vardenafil 20mg offers enhanced efficacy. While both share the same target, their pharmacodynamic profiles complement each other, leading to improved outcomes for those with erectile dysfunction.
Who Can and Cannot Take Silvitra
Silvitra is intended for adult men experiencing erectile dysfunction. Its use is generally safe for those without significant cardiovascular conditions. Men with a history of myocardial infarction, stroke, or severe arrhythmias should avoid Silvitra. Similarly, those with hypotension, severe hepatic impairment, or hereditary degenerative retinal disorders should refrain from using it.
Individuals on nitrate medication or guanylate cyclase stimulators must not use Silvitra, due to the risk of serious hypotension. Consult with a healthcare professional before starting treatment, particularly if other medications are in use or if there are pre-existing health concerns.
Missed Dose
Silvitra is taken as needed, not on a fixed schedule. A missed dose scenario typically does not apply. It is important to consume the medication approximately 30 to 60 minutes prior to anticipated sexual activity. This timing ensures optimal efficacy. Refrain from taking more than one dose in a 24-hour period.
Effects of Silvitra
The primary effect of Silvitra is the enhancement of erectile function. Successful intercourse depends on sufficient sexual stimulation alongside the drug’s action. Users may experience a fuller and longer-lasting erection. Side effects can include headache, flushing, nasal congestion, and dyspepsia.
Rare but serious side effects necessitate immediate medical attention. These include sudden vision loss, priapism, or severe hypotension. Monitor for any adverse reactions and consult a healthcare professional if concerns arise.
Purchasing Silvitra Without a Prescription
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Accessing Silvitra without a prescription poses risks. Prescription ensures appropriate usage and monitoring for contraindications. Always consult a healthcare provider before starting any new medication. Purchase from reputable sources to avoid counterfeit products, which can compromise safety and efficacy.
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